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The Changing Epidemiology of Pertussis in Acellular Vaccine Era

Barton, Jerusha Elana (2014)
Master's Thesis (125 pages)
Committee Chair / Thesis Advisers: Orenstein, Walter; Omer, Saad B
Committee Members: Bednarczyk, Robert A
Research Fields: Health Sciences, Epidemiology; Health Sciences, Public Health
Partnering Agencies: CDC ; Emory University schools, faculty or affiliated programs ; US (Federal) agency other than CDC
Keywords: Pertussis; Vaccination; Epidemiology; Infants, Adolescents, Adults; Whooping cough
Program: Rollins School of Public Health, Epidemiology (Epidemiology)
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Table of Contents


application/pdf The Changing Epidemiology of Pertussis in the Vaccine Era 125 pages (976.8 KB) [Despite high levels of vaccination, pertussis continues to circulate in the U.S. Immunity, whether naturally acquired or vaccine-induced, wanes, leading all age groups to be susceptible and capable of transmitting pertussis to infants. For this reason, we still see high rates of hospitalizations in infants. However, there has been a rise in pertussis hospitalizations in all age groups--except for infants--during and following the change to acellular vaccines. Many factors of vaccine immunity, carriage, and transmission warrant research into new vaccines and/or a change to the current immunization schedule.]
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